Louis Harold Gray

Louis Harold Gray (10 November 1905 - 9 July 1965) was a physicist who worked mainly on the effects of radiation on biological systems, inventing the field of radiobiology as he went. A summary of his work is given below. Amongst many other achievments, he defined a unit of radiation dosage which was later named after him as an SI unit, the Gray.

Summary of Career

• 1933 Hospital physicist at Mount Vernon Hospital, London
• 1936 Developed the Bragg-Gray equation, the basis for the cavity ionization method of measuring gamma-ray energy absorption by materials
• 1937 Built an early neutron generator at Mount Vernon used
• 1938 Studied biological effects of neutrons using the generator
• 1940 Developed concept of RBE (Relative Biological Effectiveness) of doses of neutrons
• 1952 Initiated research into cells in hypoxic tumors and hyperbaric oxygen
• 1953 Set up Gray Laboratory at Mount Vernon Hospital
• 1953 - 1960 Under Gray’s direction, Jack W. Boag developed pulse radiolysis
• 1962 Ed Hart (ANL) and Boag discovered the hydrated electron using pulse radiolysis at Gray Lab

This discovery initiated an new direction for chemistry research that is still very active today and is vital for understanding of the effects of radiation on biological tissue, for instance in cancer treatment.

Based in part on this slide and several subsequent and prior ones, with permission.

See also

• Definition of RBE.
• The LH Gray Memorial Trust founded in 1967
• A biography

Referenced By